Clinical Evidence Library

HBOT Case Studies & Clinical Evidence

Peer-reviewed evidence summaries for the conditions we treat with hyperbaric oxygen therapy.

Avascular Necrosis & HBOT

UHMS Recognized

Avascular necrosis (AVN), or osteonecrosis, results from disrupted blood supply to bone — most commonly affecting the...

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Chronic Refractory Osteomyelitis & HBOT

FDA & CMS Approved

Chronic refractory osteomyelitis is defined as infection that persists or recurs after appropriate surgical and antib...

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Compromised Skin Grafts & Flaps — HBOT

FDA & CMS Approved

Compromised skin grafts and flaps share a common mechanism of failure: inadequate oxygen delivery to the wound margin...

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Diabetic Foot Ulcers & HBOT

FDA & CMS Approved

Diabetic foot ulcers affect 15–25% of all diabetic patients and are the leading cause of non-traumatic lower extremit...

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Osteoradionecrosis of the Jaw & HBOT

FDA & CMS Approved — Marx Protocol

Osteoradionecrosis (ORN) of the jaw is one of the most devastating complications of head and neck radiotherapy — resu...

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Radiation Cystitis (Hemorrhagic) & HBOT

FDA & CMS Approved

Radiation cystitis is a debilitating late complication of pelvic radiotherapy — occurring in 10–15% of patients treat...

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Radiation Proctitis & HBOT

FDA & CMS Approved

Chronic radiation proctitis is a progressive, ischemic injury to the rectal mucosa caused by pelvic radiotherapy. Pat...

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Sudden Sensorineural Hearing Loss & HBOT

UHMS Recognized — Time-Critical

Sudden sensorineural hearing loss (SSHL) is a medical emergency defined as ≥30 dB loss across 3 frequencies within 72...

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